TECENTRIQ® is the first FDA-approved anti-PDL1 cancer immunotherapy to help fight this type of bladder cancer (advanced urothelial carcinoma). 2 TECENTRIQ is a medicine designed to treat your bladder cancer and is thought to work with your body’s own immune system to fight cancer cells. It may also affect normal cells.
Your role on the healthcare team
As a caregiver, you may be a vital member of your family member or friend’s healthcare team. Here are a few tips that may be helpful to you and your loved one:
- Write down any questions that either of you would like to ask the healthcare team.
- Offer to go with your family member or friend to medical appointments.
- Find out if there are any special instructions and treatment tips the healthcare team recommends.
- Reach out to family and friends that may want to help with the tasks associated with caregiving.
- Keep track of medical information and appointments.
- Note any changes in symptoms or side effects.
Learn more about how to care for someone with advanced cancer
THE VALUE OF COMMUNICATION
Communication with your loved one is one of the most valuable tools you have. The more you know about your loved one and how they are feeling, the better prepared you will be to help them. Your support is valuable and sometimes just being there to talk and listen can make a big difference.
Here are a few tips for creating a healthy dialog:
- Ask if it’s a good time to talk.
- Be supportive, listen, and avoid interrupting.
- Practice what you will say in advance.
- Speak from the heart.
- Remember that you can have more than one talk.
- Don’t always say “It’ll be okay.”
ORGANIZATIONS AND SUPPORT GROUPS
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IMPORTANT SAFETY INFORMATION AND INDICATION
TECENTRIQ is a prescription medicine used to treat:
a type of bladder and urinary tract cancer called urothelial carcinoma.
- TECENTRIQ may be used when your bladder cancer:
- has spread or cannot be removed by surgery (advanced urothelial carcinoma), and
- you are not able to take chemotherapy that contains a medicine called cisplatin, or
- you have tried chemotherapy that contains platinum, and it did not work or is no longer working
It is not known if TECENTRIQ is safe and effective in children. The approval of TECENTRIQ in these patients is based on a study that measured response rate and duration of response. There is an ongoing study to confirm clinical benefit.
What is the most important information about TECENTRIQ?
TECENTRIQ can cause your immune system to attack normal organs and tissues in many areas of your body and can affect the way they work. These problems can sometimes become serious or life threatening and can lead to death.
Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may delay or completely stop treatment with TECENTRIQ if you have severe side effects.
Call or see your healthcare provider right away if you get any symptoms of the following problems or these symptoms get worse.
TECENTRIQ can cause serious side effects, including:
- Lung problems (pneumonitis)–signs and symptoms may include new or worsening cough, shortness of breath, and chest pain
- Liver problems (hepatitis)–signs and symptoms of hepatitis may include yellowing of your skin or the whites of your eyes, severe nausea or vomiting, pain on the right side of your stomach area (abdomen), drowsiness, dark urine (tea colored), bleeding or bruising more easily than normal, and feeling less hungry than usual
- Intestinal problems (colitis)–signs and symptoms of colitis may include diarrhea (loose stools) or more bowel movements than usual, blood in your stools or dark, tarry, sticky stools, and severe stomach area (abdomen) pain or tenderness
- Hormone gland problems (especially the pituitary, thyroid, adrenal glands, and pancreas)–signs and symptoms that your hormone glands are not working properly may include headaches that will not go away or unusual headaches, extreme tiredness, weight gain or weight loss, dizziness or fainting, feeling more hungry or thirsty than usual, hair loss, changes in mood or behavior (such as decreased sex drive, irritability, or forgetfulness), feeling cold, constipation, your voice gets deeper, urinating more often than usual, nausea or vomiting, and stomach area (abdomen) pain
- Nervous system problems (neuropathy, meningitis, encephalitis)–signs and symptoms of nervous system problems may include severe muscle weakness, numbness or tingling in hands and feet, fever, confusion, changes in mood or behavior, extreme sensitivity to light, and neck stiffness
- Inflammation of the eyes–signs and symptoms may include blurry vision, double vision, or other vision problems, and eye pain or redness
- Severe infections–signs and symptoms of infection may include fever, cough, frequent urination, flu-like symptoms, and pain when urinating
- Severe infusion reactions–signs and symptoms of infusion reactions may include chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, fever, feeling like passing out, back or neck pain, and swelling of your face or lips
Before you receive TECENTRIQ, tell your healthcare provider about all your medical conditions, including if you:
- Have immune system problems (such as Crohn’s disease, ulcerative colitis, or lupus); have had an organ transplant; have lung or breathing problems; have liver problems; have a condition that affects your nervous system (such as myasthenia gravis or Guillain-Barré syndrome); or are being treated for an infection
- Are pregnant or plan to become pregnant
- TECENTRIQ can harm your unborn baby
- If you are able to become pregnant, you should use an effective method of birth control during your treatment and for at least 5 months after the last dose of TECENTRIQ
- Are breastfeeding or plan to breastfeed
- It is not known if TECENTRIQ passes into your breast milk
- Do not breastfeed during treatment and for at least 5 months after the last dose of TECENTRIQ
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of TECENTRIQ in people with urothelial carcinoma include:
- Feeling tired
- Decreased appetite
- Urinary tract infection
TECENTRIQ may cause fertility problems in females, which may affect the ability to have children. Talk to your healthcare provider if you have concerns about fertility.
These are not all the possible side effects of TECENTRIQ. Ask your healthcare provider or pharmacist for more information.